Simple Sis is a 1927 American silent comedy-melodrama directed by Herman C. Raymaker and starring Louise Fazenda as a poor, plain laundress hoping for romance, supported by Clyde Cook as a shy suitor and Myrna Loy as a cruel beauty. No copies of Simple Sis are known to exist; it is presumed lost.
Featured Crew
| Darryl F. Zanuck | Story |
| John Daumery | Assistant Director |
| Frank Kesson | Cinematography |
| Albert Kenyon | Writer |
| Herman C. Raymaker | Director |
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